GENERAL CATALOGUE
GSK143
HY-12736 · 50 mg
MedChemExpress · Cat: HY-12736
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Catalog No: HY-12736
CAS No: 1240390-27-5
Category: MAPK ERK Pathway
Pack Size: 50 mg
Brand: MedChemExpress
Description
GSK143 is an orally active and highly selective spleen tyrosine kinase SYK inhibitor with a pIC50 of 7.5. GSK143 inhibits phosphorylated Erk pErk: pIC50=7.1 . GSK143 reduces inflammation and prevents recruitment of immune cells in the intestinal muscularis in mice.
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