GENERAL CATALOGUE
GSK180
HY-112179 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-112179
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Manufacturer product page
medchemexpress.com/gsk180.htmlCatalog No: HY-112179
CAS No: 1799725-26-0
Category: Metabolic Enzyme Protease
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
GSK180 is a selective, competitive, and potent inhibitor of kynurenine-3-monooxygenase KMO , a key enzyme of tryptophan metabolism IC50, 6 nM , but shows negligible activity against other enzymes on the tryptophan pathway. GSK180 rapidly changes levels of kynurenine pathway metabolites, and acts as a useful tool to probe the therapeutic potential of KMO inhibition.
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