GENERAL CATALOGUE
GSK2194069
HY-12325 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-12325
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Catalog No: HY-12325
CAS No: 1332331-08-4
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
GSK2194069 is a potent inhibitor of ?-ketoyl reductase KR of fatty acid synthase FASN , with an IC50 value of 7.7 nM. GSK2194069 shows specifically inhibitory effect on FAS expressing cancer cells, by acting potent efficacy on acetoacetyl-CoA, NADPH with IC50 or Ki values of 4.8 nM and 5.6 nM, respectively.
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