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GSK3368715 dihydrochloride
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GSK3368715 dihydrochloride

HY-128717A · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-128717A

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Catalog No: HY-128717A
CAS No: 1628925-77-8
Category: Epigenetics
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

GSK3368715 dihydrochloride EPZ019997 dihydrochloride is an orally active, reversible, and S-adenosyl-L-methionine SAM uncompetitive type I protein arginine methyltransferases PRMTs inhibitor IC50=3.1 nM PRMT1 , 48 nM PRMT3 , 1148 nM PRMT4 , 5.7 nM PRMT6 , 1.7 nM PRMT8 . GSK3368715 dihydrochloride EPZ019997 dihydrochloride produces a shift in arginine methylation states, alters exon usage, and has strong anti-cancer activity.

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