

HY-150080 · 50 mg
MedChemExpress · Cat: HY-150080
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medchemexpress.com/gsk3739936.htmlDescription
GSK3739936 BMS-986180 is a potent HIV-1 allosteric integrase inhibitor with an IC50 value of 11.1 nM and an EC50 value of 1.7 nM. GSK3739936 is also a weak CYP inhibitor IC50 24.3 ?M. GSK3739936 shows favorable pharmacokinetic property in preclinical species with rapid absorption, low to moderate clearance and excellent oral bioavailability.







