GENERAL CATALOGUE
GSK4418959
HY-169422 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-169422
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Manufacturer product page
medchemexpress.com/wrn-inhibitor-16.htmlCatalog No: HY-169422
CAS No: 3064599-36-3
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
GSK4418959 IDE275 is a selective, reversible and orally active WRN helicase inhibitor. GSK4418959 shows >10,000-fold selectivity over other helicases. GSK4418959 inhibits ATPase and DNA unwinding functions in an ATP-competitive manner. GSK4418959 can be used for the study of microsatellite instability-high MSI-H cancer, such as colorectal cancer CRC and endometrial cancer EC .
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