GENERAL CATALOGUE
GSK481
HY-100131 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-100131
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Manufacturer product page
medchemexpress.com/GSK_acute_481.htmlCatalog No: HY-100131
CAS No: 1622849-58-4
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
GSK481 is a highly potent, selective, and specific receptor interacting protein 1 RIP1 kinase inhibitor with an IC50 of 1.3 nM, which inhibits Ser166 phosphorylation in wild-type human RIP1 IC50=2.8 nM . GSK481 also exhibits excellent translation in the U937 cellular assay with an IC50 of 10 nM.
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