

HY-103018 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-103018
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Manufacturer product page
medchemexpress.com/ASN-002.html
Description
Gusacitinib ASN-002 is an orally active dual SYK/JAK kinase inhibitor with IC50 values of 5, 46, 4, 11 and 8 nM for SYK, JAK1, JAK2, and , respectively. Gusacitinib rapidly and significantly suppressed key inflammatory pathways implicated in atopic dermatitis pathogenesis. Gusacitinib can be used in the research of chronic hand eczema and cancers such as basal cell carcinoma.

