GENERAL CATALOGUE
GW274150 dihydrochloride
HY-12119B · 50 mg
MedChemExpress · Cat: HY-12119B
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medchemexpress.com/gw274150-dihydrochloride.htmlCatalog No: HY-12119B
CAS No: 438542-17-7
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
GW274150 dihydrochloride is a potent, selective, orally active and NADPH-dependent inhibitor of human inducible nitric oxide synthase iNOS IC50=2.19 ?M; Kd=40 nM and rat iNOS ED50=1.15 ?M . GW274150 dihydrochloride displays less potency for both humans or rats endothelial NOS eNOS and neuronal NOS nNOS . GW274150 dihydrochloride exerts a protective role in an acute model of lung injury inflammation.
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