GENERAL CATALOGUE
GW274150
HY-12119 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-12119
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medchemexpress.com/GW274150.htmlCatalog No: HY-12119
CAS No: 210354-22-6
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
GW274150 is a potent, selective, orally active and NADPH-dependent inhibitor of human inducible nitric oxide synthase iNOS IC50=2.19 ?M; Kd=40 nM and rat iNOS ED50=1.15 ?M . GW274150 also displays less potency for both humans or rats endothelial NOS eNOS and neuronal NOS nNOS . GW274150 exerts a protective role in an acute model of lung injury inflammation.
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