GENERAL CATALOGUE
GW406108X
HY-115570 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-115570
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medchemexpress.com/gw406108x.htmlCatalog No: HY-115570
CAS No: 1644443-92-4
Category: Autophagy
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
GW406108X is a specific Kif15 Kinesin-12 inhibitor with an IC50 of 0.82 uM in ATPase assays. GW406108X, a potent autophagy inhibitor, shows ATP competitive inhibition against ULK1 with a pIC50 of 6.37 427 nM . GW406108X inhibits ULK1 kinase activity and blocks autophagic flux, without affecting the upstream signaling kinases mTORC1 and AMPK.
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