

HY-138559 · 5 mg
MedChemExpress · Cat: HY-138559
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medchemexpress.com/gw604714x.htmlDescription
GW604714X is a potent inhibitor of mitochondrial respiration supported by pyruvate but not other substrates. GW604714X is a highly specific mitochondrial pyruvate carrier MPC inhibitor with a Ki 0.1 nM. GW604714X also inhibits L-lactate transport by the plasma membrane monocarboxylate transporter MCT1 , but at concentrations more than 4 orders of magnitude greater than the MPC.