GENERAL CATALOGUE
GW779439X
HY-103645 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-103645
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medchemexpress.com/gw779439x.htmlCatalog No: HY-103645
CAS No: 551919-98-3
Category: Anti-infection
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
GW779439X is a pyrazolopyridazine identified in an inhibitor of the S. aureus PASTA kinase Stk1. GW779439X potentiates the activity of ?-lactam antibiotics against various MRSA and MSSA isolates, some even crossing the breakpoint from resistant to sensitive. GW779439X is an AURKA inhibitor and induces apoptosis by the caspases 3/7 pathway. MRSA:methicillin-resistant S. aureus; MSSA: methicillin-sensitive S. aureus
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