GENERAL CATALOGUE
H052
HY-173526 · 50 mg
MedChemExpress · Cat: HY-173526
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medchemexpress.com/h052.htmlCatalog No: HY-173526
CAS No: 2886748-00-9
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
H052 is a selective Staphylococcus aureus ?-hemolysin Hla inhibitor. H052 binds to Hla monomers, disrupts the interaction with host cell membranes to block pore formation, inhibiting calcium ion influx, cytotoxicity, and inflammatory responses. H052 exhibits potency EC50=30 nM in U937 cells against Hla-induced calcium influx. H052 is promising for research of lung infections caused by S. aureus.