H
GENERAL CATALOGUE
H295RA Cells
T8243 · 1 x 106 cells / 1.0 mL
abm good · Cat: T8243
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Catalog No: T8243
Category: Cellular Materials
Pack Size: 1 x 106 cells / 1.0 mL
Brand: abm good
Description
H295RA is an ACTH-responsive human adrenocortical cell line, produced from H295R cells that have been transduced to stable express increased human MRAP MC2R accessory protein gene. H295R adrenocortical cell line displays relatively low ACTH responsiveness due to low melanocortin 2 receptor MC2R expression. Successful induction of MRAP and increased expression of MC2R in H295RA cells was confirmed by quantitative real-time RT-PCR and protein analysis. This cell line is well-suited for research regarding molecular analysis of physiologic and pathologic conditions involving the hypothalamicpituitaryadrenal axis.
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