

HY-146383 · 50 mg
MedChemExpress · Cat: HY-146383
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medchemexpress.com/h3r-antagonist-2.htmlDescription
H3R antagonist 2 Compound 23 is a multitarget histamine H3 receptor H3R antagonist with a Ki of 170 nM for hH3R . H3R antagonist 2 shows inhibitory effects with IC50 values of 180, 880 and 775 nM for acetylcholinesterase, butyrylcholinesterase and human monoamine oxidase B hMAO B , respectively. H3R antagonist 2 shows favorable anti-neuropathic pain and memory-enhancing effects. H3R can across BBB.







