GENERAL CATALOGUE
HaloPROTAC-E
HY-145752 · 1 mg
MedChemExpress · Cat: HY-145752
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medchemexpress.com/haloprotac-e.html
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Catalog No: HY-145752
CAS No: 2365478-58-4
Category: Autophagy
Pack Size: 1 mg
Brand: MedChemExpress
Description
HaloPROTAC-E is a potent Halo PROTAC degrader that reversibly induces degradation of two Halo-tagged endoplasmic reticulum-localized proteins, SGK3 and VPS34, with a DC50 of 3-10 nM. HaloPROTAC-E significantly and selectively induces degradation of endogenous VPS34 complexes VPS34, VPS15, Beclin1, and ATG14 labeled with Halo and inhibits autophagy.
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