GENERAL CATALOGUE
HbF inducer 2
HY-159099 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-159099
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Catalog No: HY-159099
CAS No: 2654011-51-3
Category: Epigenetics
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
HbF inducer 3 Compound dWIZ-2 is an orally active molecular glue, which degrades the WIZ transcription factor DC50=13 nM in primary human erythroid precursor cell and induces the expression of fetal hemoglobin HbF EC50=100 nM . HbF inducer 3 exhibits good pharmacokinetic characteristics in cynomolgus monkeys.
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