GENERAL CATALOGUE
HBI-2375
HY-175802 · 50 mg
MedChemExpress · Cat: HY-175802
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medchemexpress.com/hbi-2375.htmlCatalog No: HY-175802
CAS No: 2982574-79-6
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
HBI-2375 HYBI-084 is a selective, brain-penetrant and orally active MLL1-WDR5 interaction inhibitor. HBI-2375 inhibits WDR5 with an IC50 of 4.48 nM. HBI-2375 shows inhibition of proliferation in MV4;11 leukemia cells IC50: 3.17 AAasAasAAmuM . HBI-2375 is capable of targeted disruption of histone methyltransferase activity in cancer cells. HBI-2375 can be used for the study of leukemia, glioma and glioblastoma.