HBP1 Rabbit Polyclonal Antibody

Description

EnkiLife offers the HBP1 Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse,Rat,Monkey species and is suitable for WB,IHC,ICC/IF,ELISA application. Alternative Names of Immunogen: HBP1; HMG box-containing protein 1; HMG box transcription factor 1; High mobility group box transcription factor 1. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:5000-1:20000 Background: function:Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. similarity:Contains 1 AXH domain. similarity:Contains 1 HMG box DNA-binding domain. subunit:Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1.