

ab120554 · 10 mg
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Description
MW 355.4 Da, Purity >99 %. Selective TRPA1 blocker, orally active. Blocks TRPA1-mediated currents IC50 = 0.7 muM and selective over TRPV1, TRPV3, TRPV4, hERG, and NaV1.2 channels IC50 10 muM. Does not display any significant binding to 41 other receptors, ion channels, and transporters nor functional modulation of 7 enzymes that are known to modulate pain signaling.






