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hCAIX/XII-IN-13
GENERAL CATALOGUE

hCAIX/XII-IN-13

HY-162000 · 50 mg

MedChemExpress · Cat: HY-162000

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Catalog No: HY-162000
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

hCAIX/XII-IN-13 is an inhibitor of human carbonic anhydrases hCA . hCAIX/XII-IN-13 shows good inhibitory activity against the tumor-related CA subtypes IX and XII, with Ki values of 0.08 AAasAasAAmuM and 0.06 AAasAasAAmuM, respectively. Under hypoxic conditions, hCAIX/XII-IN-13 can restore the cytotoxicity of Doxorubicin HY-15142A on MCF-7 cells, increasing G2/M phase cell cycle arrest and apoptosis.

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