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hCAIX/XII-IN-8
GENERAL CATALOGUE

hCAIX/XII-IN-8

HY-156181 · 50 mg

MedChemExpress · Cat: HY-156181

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Catalog No: HY-156181
CAS No: 59994-64-8
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress

Description

hCAIX/XII-IN-8 compound 3g is a potent human carbonic anhydrase CA IX and XII inhibitor, with Ki values of 8.5 and 6.7 nM, respectively. hCAIX/XII-IN-8 shows particularly strong inhibitory activity against the tumor-associated membrane-bound isoforms, hCA IX and XII, while maintaining a high selectivity ratio over cytosolic off-target isoforms hCA I and II.

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