

HY-156181 · 50 mg
MedChemExpress · Cat: HY-156181
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medchemexpress.com/hcaix-xii-in-8.htmlDescription
hCAIX/XII-IN-8 compound 3g is a potent human carbonic anhydrase CA IX and XII inhibitor, with Ki values of 8.5 and 6.7 nM, respectively. hCAIX/XII-IN-8 shows particularly strong inhibitory activity against the tumor-associated membrane-bound isoforms, hCA IX and XII, while maintaining a high selectivity ratio over cytosolic off-target isoforms hCA I and II.







