GENERAL CATALOGUE
HCAR2 agonist 1
HY-156025 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-156025
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medchemexpress.com/hcar2-agonist-1.htmlCatalog No: HY-156025
CAS No: 1066676-21-8
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
HCAR2 agonist 1 Compound 9n is a Gi protein-biased allosteric modulator of HCAR2. HCAR2 agonist 1 activates the Gi protein signaling pathway. HCAR2 agonist 1 shows anti-inflammatory effect, and reduces mRNA level of pro-inflammatory cytokine TNF-?, IL-1?, IL-6, and MCP-1 . HCAR2 agonist 1 enhances anti-inflammatory effects of orthosteric agonists in the mouse model of colitis.
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