HCV-IN-45

Description

HCV-IN-45 Compound EI-1 is an inhibitor for hepatitis C virus HCV , that inhibits 1a and 1b HCV pseudoparticles with EC50 of 0.134 and 0.027 ?M. HCV-IN-45 inhibits 1a/2a and 1b/2a cell culture-adapted HCV HCVcc , with EC50 of 0.024 and 0.012?M. HCV-IN-45 inhibits the entry of the virus into hepatocyte, and blocks the cell-cell spread.