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HDAC/HSP90-IN-3
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HDAC/HSP90-IN-3

HY-144694 · 50 mg

MedChemExpress · Cat: HY-144694

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Catalog No: HY-144694
CAS No: 2700035-54-5
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress

Description

HDAC/HSP90-IN-3 compound J5 is a potent and selective fungal Hsp90 and HDAC dual inhibitor, with IC50 values of 0.83 and 0.91 ?M, respectively. HDAC/HSP90-IN-3 shows antifungal activity against azole resistant C. albicans. HDAC/HSP90-IN-3 can suppress important virulence factors and down-regulate drug-resistant genes ERG11 and CDR1.

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