GENERAL CATALOGUE
HDAC/HSP90-IN-4
HY-146212 · 50 mg
MedChemExpress · Cat: HY-146212
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medchemexpress.com/hdac-hsp90-in-4.htmlCatalog No: HY-146212
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
These compounds have strong hdac and hsp90 inhibitory activities. Compound 20 HDAC ic50 ? = ? 194 ? nm; Hsp90 ? b Ic50 = ? 153 ? nm and compound 26 HDAC ic50= ? 360 ? nm; Hsp90 ? < b Ic50 ? = ? 77 ? nm shows the strongest HDAC and HSP90 ? Inhibitory activity. Both compounds can induce hsp90 expression and down regulate hsp90 client proteins, which play an important role in regulating the survival and invasion of cancer cells.
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