GENERAL CATALOGUE
HDAC-IN-46
HY-150597 · 50 mg
MedChemExpress · Cat: HY-150597
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medchemexpress.com/hdac-in-46.htmlCatalog No: HY-150597
CAS No: 2562386-85-8
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
HDAC-IN-46 compound 12c is a potent HDAC inhibitor with an IC50 value of 0.21 ?M and 0.021 ?M for HDAC1 and HDAC6, respectively. HDAC-IN-46 upregulates p-p38, and downregulates Bcl-xL and cyclin D1 in MDA-MB-231 cells. HDAC-IN-46 induces significant G2 phase arrest and apoptosis. HDAC-IN-46 can be used for researching triple-negative breast cancer TNBC .
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