GENERAL CATALOGUE
HDAC-IN-56
HY-154855 · 50 mg
MedChemExpress · Cat: HY-154855
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medchemexpress.com/hdac-in-56.htmlCatalog No: HY-154855
CAS No: 2814571-89-4
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
HDAC-IN-56 S -17b is an orally active class I histone deacetylase HDAC inhibitor with IC50 values of 56.0 AAasAasAA+/- 6.0, 90.0 AAasAasAA+/- 5.9, 422.2 AAasAasAA+/- 105.1, >10000 nM for HDAC1, HDAC2, HDAC3, and HDAC4-11, respectively. HDAC-IN-56 has potent inhibitory activity while strongly increasing intracellular levels of acetylhistone H3 and P21 and effectively inducing G1 cell cycle arrest and apoptosis.HDAC-IN-56 has antitumor activity .
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