

HY-161984 · 50 mg
MedChemExpress · Cat: HY-161984
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medchemexpress.com/hdac-in-76.htmlDescription
HDAC-IN-76 compound 6i is a histone deacetylase HDAC inhibitor. HDAC-IN-76 IC50 values of 30 nM and 98 nM for Pf3D7 chloroquine HY-17589A drug-susceptible strain and PfDd2 chloroquine HY-17589A drug-resistant strain , has a highly potent antimalarial activity against asexual blood-stage Plasmodium, respectively, and exhibits selective inhibition against parasites, with IC50 values of 7 nM and 9 nM for human HDAC1 and HDAC6, respectively, while inhibiting PfHDAC1.





