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HDAC1/CDK7-IN-1
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HDAC1/CDK7-IN-1

HY-156444 · 50 mg

MedChemExpress · Cat: HY-156444

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Catalog No: HY-156444
CAS No: 2987905-95-1
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

HDAC1/CDK7-IN-1 compound 8e is a dual CDK7 and HDAC1 inhibitor with IC50s of 893 nM and 248 nM, respectively. HDAC1/CDK7-IN-1 inhibits the growth cells of MDA-MB-231, MCF-7, A549, and HCT-116 cancer cells. HDAC1/CDK7-IN-1 induces cell cycle arrest and apoptosis in HCT-116 cells, as well as hindered the migration of HCT-116 cells.

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