GENERAL CATALOGUE
HDAC1-IN-5
HY-151153 · 50 mg
MedChemExpress · Cat: HY-151153
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Manufacturer product page
medchemexpress.com/hdac1-in-5.htmlCatalog No: HY-151153
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
HDAC1-IN-5 is a potent HDAC1 inhibitor with IC50 values of 15 nM and 20 nM for HDAC1 and HDAC6, respectively. HDAC1-IN-5 can enhance the acetylation of histone H3 and ?-tubulin, as well as promote the activation of caspase 3 in cancer cells, thereby inducing apoptosis. HDAC1-IN-5 induces chromatin damage by binding with DNA. HDAC1-IN-5 has strong inhibitory activity against tumor growth in xenograft mice.
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