HDAC2 (2D9) Mouse Monoclonal Antibody

Description

EnkiLife offers the HDAC2 (2D9) Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat,Monkey species and is suitable for WB,ICC/IF application. Alternative Names of Immunogen: HDAC2; Histone deacetylase 2; HD2. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,ICC/IF 1:50-1:200 Background: In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Research Area: Epigenetics and Nuclear Signaling