GENERAL CATALOGUE
HDAC3/BRD4-IN-1
HY-170841 · 50 mg
MedChemExpress · Cat: HY-170841
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Manufacturer product page
medchemexpress.com/hdac3-brd4-in-1.htmlCatalog No: HY-170841
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
HDAC3/BRD4-IN-1 compound 26n is an inhibitor of HDAC3/BRD4 with an IC50 of 8 nM for HDAC3 IC50s are 220 nM and 120 nM for HDAC1 and HDAC2, respectively . HDAC3/BRD4-IN-1 has anti-tumor and anti-proliferative effects by upregulating Ac-H3 and downregulating c-Myc. The half-life of HDAC3/BRD4-IN-1 in human liver microsomes is 29.36 min.
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