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HDAC6/HSP90-IN-1
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HDAC6/HSP90-IN-1

HY-146293 · 50 mg

MedChemExpress · Cat: HY-146293

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Catalog No: HY-146293
CAS No: 2411955-43-4
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress

Description

HDAC6/HSP90-IN-1 compound 17 is a potent and selective dual inhibitor of HDAC6 and HSP90, with IC50 values of 4.3 and 46.8 nM, respectively. HDAC6/HSP90-IN-1 down-regulates PD-L1 expression in INF-? treated H1975 lung cancer cells. HDAC6/HSP90-IN-1 inhibits tumor growth in human H1975 xenograft mice.

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