GENERAL CATALOGUE
HDACs/EZH2-IN-1
HY-169400 · 50 mg
MedChemExpress · Cat: HY-169400
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Manufacturer product page
medchemexpress.com/hdacs-ezh2-in-1.htmlCatalog No: HY-169400
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
HDACs/EZH2-IN-1 Compound 22a is a HDACs/EZH2 inhibitor EZH2 Y641N inhibition rate at 50 nM: 98 % , with selective inhibition against HDAC1 and HDAC6 IC50: 0.23 ?M and 0.07 ?M, respectively . HDACs/EZH2-IN-1 exerts a antiproliferative effect on diffuse large B-cell lymphoma cells harboring an EZH2 mutation and on various acute myeloid leukemia cells. HDACs/EZH2-IN-1 has the ability to induce cell differentiation and Apoptosis.
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