GENERAL CATALOGUE
HDM-IN-1
HY-169919 · 50 mg
MedChemExpress · Cat: HY-169919
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medchemexpress.com/hdm-in-1.htmlCatalog No: HY-169919
CAS No: 3020690-76-7
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
HDM-IN-1 Compound A4 is an inhibitor for fungal histone demethylase HDM , that inhibits the H3K27me3 in Cryptococcus neoformans and in Candida auris with IC50s of 134 and 12 nM. HDM-IN-1 exhibits inhibitory efficacy against C. neoformans and C. auris with MIC80 of 0.5-2 ?g/mL, through inhibition of the biofilm and capsule formation. HDM-IN-1 exhibits antifungal activity in ICR mouse model.
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