GENERAL CATALOGUE
HDSI-18
HY-172873 · 50 mg
MedChemExpress · Cat: HY-172873
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Manufacturer product page
medchemexpress.com/hdsi-18.htmlCatalog No: HY-172873
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
HDSI-18 is an orally active HDAC6 selective inhibitor IC50: 1.6 nM . HDSI-18 is cytotoxic to K562, MV4-11, MOLM-13, THP-1, and Jurkat cells IC50: 0.48, 0.58, 0.91, 1.79, and 4.31 ?M, respectively . HDSI-18 activates Caspase-3, induces mitochondrial depolarization and apoptosis, and has antitumor activity.
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