GENERAL CATALOGUE
HEC96719
HY-153114 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-153114
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Catalog No: HY-153114
CAS No: 2181834-03-5
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
HEC96719 is a selective and orally active tricyclic farnesoid X receptor FXR agonist with EC50 values of 1.37 and 1.55 nM by time-resolved fluorescence energy transfer TR-FRET and luciferase reporter assays, respectively. HEC96719 significantly improves non-alcoholic steatohepatitis NASH and liver fibrosis with favorable tissue distribution in liver and intestine. HEC96719 can be used for the research of non-alcoholic steatohepatitis.
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