GENERAL CATALOGUE
HEMTAC WEE1 degrader-1
HY-173320 · 50 mg
MedChemExpress · Cat: HY-173320
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medchemexpress.com/hemtac-wee1-degrader-1.htmlCatalog No: HY-173320
CAS No: 3002417-64-0
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
HEMTAC WEE1 degrader-1 is a HSP90-mediated targeting chimera HEMTAC degrader of WEE1 HSP90 enzyme inhibitory activity is IC50: 16.76 nM . HEMTAC WEE1 degrader-1 promotes the ubiquitination and degradation of WEE1. HEMTAC WEE1 degrader-1 blocks the G2/M cell cycle. HEMTAC WEE1 degrader-1 has anticancer activity in acute myeloid leukemia AML patient-derived xenograft PDX models. HEMTAC WEE1 degrader-1 can be used in AML research. Pink: HSP90 binder; Blue: WEE1 ligand; Black: linker .
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