Heptadecanoyl L-carnitine-d3 HCl

Description

Heptadecanoyl L-carnitine-d3 HCl is the deuterium labeled R,R,S -GAT107 HY-167922 . R,R,S -GAT107 is a fully agonistic positive modulator of ?7 nicotinic receptors with significant biological activity. Its activity is entirely present in its + -isomer 1b, while - -isomer 1a does not affect its activity when used together. Studies have shown that R,R,S -GAT107 is the most potent ago-PAM for ?7 nicotinic receptors currently known and has the potential for further in vivo evaluation.