

HY-175289 · 50 mg
MedChemExpress · Cat: HY-175289
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medchemexpress.com/herg-in-3.htmlDescription
hERG-IN-3 is an orally active hERG blocker with an IC50 of 44.5 nM. hERG-IN-3 exhibits a Ki for ?2-adrenergic receptor of 14 nM. hERG-IN-3 exhibits the skeletal muscle Nav1.4 and sodium channel-blocking activities IC50 = 4.4 ?M, 3-fold increasement than hNav1.5 . hERG-IN-3 displays a potent antimyotonic activity in an animal model. hERG-IN-3 can be used for the study of Myotonia Congenita.







