GENERAL CATALOGUE
HET0016
HY-124527 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-124527
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Catalog No: HY-124527
CAS No: 339068-25-6
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
HET0016 is a potent and selective 20-hydroxyeicosatetraenoic acid 20-HETE synthase inhibitor, with IC50 values of 17.7 nM, 12.1 nM and 20.6 nM for recombinant CYP4A1-, CYP4A2- and CYP4A3-catalyzed 20-HETE synthesis, respectively. HET0016 also is a selective CYP450 inhibitor, which has been shown to inhibit angiogenesis and tumor growth.
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