GENERAL CATALOGUE
Higenamine hydrochloride
HY-N2037A · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-N2037A
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Catalog No: HY-N2037A
CAS No: 11041-94-4
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Higenamine hydrochloride is a selective LSD1 inhibitor IC50=1.47 ?M that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine Norcoclaurine can attenuate IL-1?-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine hydrochloride protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine hydrochloride can be used to study cancer, inflammation, cardiorenal syndrome and other diseases.
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