Histone H2A Rabbit Monoclonal Antibody

Description

EnkiLife offers the Histone H2A Rabbit Monoclonal Antibody. This antibody reacts with Human,Rat species and is suitable for WB application. Alternative Names of Immunogen: Histone H2A.2. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000 Background: Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.