

HY-144123 · 50 mg
MedChemExpress · Cat: HY-144123
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medchemexpress.com/hiv-1-inhibitor-16.htmlDescription
HIV-1 inhibitor-16 compound 7a is a highly potent HIV-1 inhibitor with an EC50 value of 1.3 nM for HIV-1 WT. HIV-1 inhibitor-16 also has certain inhibitory activity against HIV-1 K103N, E138K, Y181C and L100I strains with EC50s of 5.4 nM, 9.2 nM, 22 nM and 35 nM. HIV-1 inhibitor-16 has favorable solubility and liver microsome stability, and does not exhibit apparent CYP enzymatic inhibitory activity or acute toxicity.







