GENERAL CATALOGUE
HIV-1 inhibitor-24
HY-146019 · 50 mg
MedChemExpress · Cat: HY-146019
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medchemexpress.com/hiv-1-inhibitor-24.htmlCatalog No: HY-146019
CAS No: 2475658-75-2
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
HIV-1 inhibitor-24 compound S-12a is a highly potent HIV-1 reverse transcriptase, with an IC50 value of 9.5 nM. HIV-1 inhibitor-24 has high antiretroviral activity against WT HIV-1 with an EC50 of 1.6 nM, and exhibits relatively low cytotoxicity with a CC50 of 9.07 ?M in MT-4 cells. HIV-1 inhibitor-24 is well tolerated at a dose of 2 g/kg in mice and has a significant cardiovascular safety.