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HIV-1 inhibitor-25
GENERAL CATALOGUE

HIV-1 inhibitor-25

HY-146019A · 50 mg

MedChemExpress · Cat: HY-146019A

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Catalog No: HY-146019A
CAS No: 2475658-74-1
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress

Description

HIV-1 inhibitor-25 compound R-12a is a highly potent HIV-1 reverse transcriptase, with an IC50 value of 0.1061 ?M. HIV-1 inhibitor-25 has high antiretroviral activity against WT HIV-1 with an EC50 of 13.6 nM, and exhibits relatively low cytotoxicity with a CC50 of 33.13 ?M in MT-4 cells. HIV-1 inhibitor-25 also has inhibitory activity against HIV-1 mutant strains L100I, K103N, Y181C, Y188L, E138K, F227L+V106A with EC50 of 0.1961 5.8136 ?M. HIV-1 inhibitor-25 can be used for researching AIDS.

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