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HIV-1 inhibitor-51
GENERAL CATALOGUE

HIV-1 inhibitor-51

HY-152161 · 50 mg

MedChemExpress · Cat: HY-152161

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Catalog No: HY-152161
CAS No: 2834087-82-8
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress

Description

HIV-1 inhibitor-51, a non-nucleoside reverse transcriptase inhibitor NNRTI , exhibits outstanding antiviral activity against WT HIV-1 IIIB and a panel of mutant strains. HIV-1 inhibitor-51 has high binding affinity KD=2.50 ?M and inhibitory activity IC50=0.03 ?M to WT HIV-1 RT. HIV-1 inhibitor-51 has EC50s of 2.22-53.3 nM for mutant strains L100I, K103N, Y181C, Y188L, E138K, F227L + V106A, RES056 .

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