

HY-152161 · 50 mg
MedChemExpress · Cat: HY-152161
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medchemexpress.com/hiv-1-inhibitor-51.htmlDescription
HIV-1 inhibitor-51, a non-nucleoside reverse transcriptase inhibitor NNRTI , exhibits outstanding antiviral activity against WT HIV-1 IIIB and a panel of mutant strains. HIV-1 inhibitor-51 has high binding affinity KD=2.50 ?M and inhibitory activity IC50=0.03 ?M to WT HIV-1 RT. HIV-1 inhibitor-51 has EC50s of 2.22-53.3 nM for mutant strains L100I, K103N, Y181C, Y188L, E138K, F227L + V106A, RES056 .







