

HY-134851 · 5 mg
MedChemExpress · Cat: HY-134851
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medchemexpress.com/hiv-1-inhibitor-6.htmlDescription
HIV-1 inhibitor-6 compound 9 , a diheteroarylamide-based compound, is a potent HIV-1 pre-mRNA alternative splicing inhibitor. HIV-1 inhibitor-6 blocks HIV replication. HIV-1 inhibitor-6 is active against wild-type HIV-1IIIB subtype B, X4-tropic and HIV-1 97USSN54 subtype A, R5-tropic with EC50s of 0.6 ?M and 0.9 ?M, respectively. HIV-1 inhibitor-6 inhibits HIV strains resistant to agents targeting HIV reverse transcriptase, protease, integrase, and coreceptor CCR5 with EC50s ranging from 0.9 to 1.5 ?M.







